Papers on genetic interactions in Nematoda

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Gunsalus KC
A Caenorhabditis elegans genetic-interaction map wiggles into view.
2008 Mar, J. Biol., 7(3):8
Caenorhabditis elegans
Byrne A. B., Weirauch M. T., Wong V., Koeva M., Dixon S. J., Stuart J. M., Roy P. J.
A global analysis of genetic interactions in Caenorhabditis elegans.
2007 Sep, J. Biol., 6:8
discovery » techniques » RNAiCaenorhabditis elegans
Lehner B.
Modelling genotype-phenotype relationships and human disease with genetic interaction networks.
2007 May, J. Exp. Biol., 210(Pt 9):1559-1566
applications » disease association studies

discovery » techniques

Saccharomyces cerevisiae, Homo sapiens, Caenorhabditis elegans
Onami S., Kitano H.
Genome-wide prediction of genetic interactions in a metazoan.
2006 Nov, Bioessays, 28(11):1087-1090
interpretation & analysisCaenorhabditis elegans
Lehner B., Crombie C., Tischler J., Fortunato A., Fraser A. G.
Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways.
2006 Aug, Nat. Genet., 38(8):896-903
discovery » techniques » RNAiCaenorhabditis elegans
Eddy S. R.
Total information awareness for worm genetics.
2006 Mar, Science, 10:1381-1382
interpretation & analysisCaenorhabditis elegans
Zhong W., Sternberg P.W.
Genome-wide prediction of C. elegans genetic interactions.
2006 Mar, Science, 311:1481-1484
discovery » techniques » computational predictionCaenorhabditis elegans
Suzuki Y., Han M.
Genetic redundancy masks diverse functions of the tumor suppressor gene PTEN during C. elegans development.
2006 Feb, Genes Dev., 20:423-428
discovery » techniques » RNAiCaenorhabditis elegans
Tischler J., Lehner B., Chen N., Fraser A. G.
Combinatorial RNA interference in C. elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution.
2006 Jan, Genome Biol., 7:R69
discovery » techniques » RNAiCaenorhabditis elegans
Baugh L. R., Wen J. C., Hill A. A., Slonim D. K., Brown E. L., Hunter C. P.
Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions.
2005 Apr, Genome Biol., 6(5):R45
discovery » techniques » RNAi

concepts » synthetic lethality

Caenorhabditis elegans
Van Haaften G., Vastehouw N. L., Nollen E. A., Plasterk R. H., Tijsterman M.
Gene interactions in the DNA damage-response pathway identified by genome-wide RNA-interference analysis of synthetic lethality.
2004 Aug, Proc. Natl. Acad. Sci. U.S.A., 101(35):12992-12996
discovery » techniques » RNAi

concepts » synthetic lethality

Caenorhabditis elegans
Fraser A.
Towards full employment: using RNAi to find roles for the redundant.
2004 Jan, Oncogene, 23:8346-8352
discovery » techniques » RNAi

applications » disease association studies » cancer

Caenorhabditis elegans

 

© 2007—2008 Anastasia Baryshnikova (a.baryshnikova@utoronto.ca), graduate student with Charlie Boone and Gary Bader at the University of Toronto.