July, 2009—August, 2008 papers on genetic interactions

July, 2009

June, 2009

Moeller BJ, Pasqualini R, Arap W
Targeting cancer-specific synthetic lethality in double-strand DNA break repair.
2009 Jun, Cell Cycle, 8 (12):
Yeh PJ, Hegreness MJ, Aiden AP, Kishony R
Drug interactions and the evolution of antibiotic resistance.
2009 Jun, Nat. Rev. Microbiol., 7 (6):460-6
Iglehart JD, Silver DP
Synthetic Lethality -- A New Direction in Cancer-Drug Development.
2009 Jun, N. Engl. J. Med.,
Cha RH, Yang SH, Kim HS, Kim SM, Park MH, Ha J, Kim YS
Genetic interactions between the donor and the recipient for susceptibility to acute rejection in kidney transplantation: polymorphisms of CCR5.
2009 Jun, Nephrol. Dial. Transplant.,

May, 2009

Achkar JP, Fiocchi C
Gene-Gene Interactions in Inflammatory Bowel Disease: Biological and Clinical Implications.
2009 May, Am. J. Gastroenterol., ():
Davis BH, Poon AF, Whitlock MC
Compensatory mutations are repeatable and clustered within proteins.
2009 May, Proc. Biol. Sci., 276 (1663):1823-7

April, 2009

Brady A, Maxwell K, Daniels N, Cowen LJ
Fault tolerance in protein interaction networks: stable bipartite subgraphs and redundant pathways.
2009 Apr, PLoS ONE, 4 (4):e5364
Dotan-Cohen D, Letovsky S, Melkman AA, Kasif S
Biological process linkage networks.
2009 Apr, PLoS ONE, 4 (4):e5313
Neher RA, Shraiman BI
Competition between recombination and epistasis can cause a transition from allele to genotype selection.
2009 Apr, Proc. Natl. Acad. Sci. U.S.A., 106 (16):6866-71
Carter GW, Galas DJ, Galitski T
Maximal extraction of biological information from genetic interaction data.
2009 Apr, PLoS Comput. Biol., 5 (4):e1000347

March, 2009

Fiedler D, Braberg H, Mehta M, Chechik G, Cagney G, Mukherjee P, Silva AC, Shales M, Collins SR, van Wageningen S, Kemmeren P, Holstege FC, Weissman JS, Keogh MC, Koller D, Shokat KM, Krogan NJ
Functional organization of the S. cerevisiae phosphorylation network.
2009 Mar, Cell, 136 (5):952-63

February, 2009

Veeramani B, Bader JS
Metabolic flux correlations, genetic interactions, and disease.
2009 Feb, J. Comput. Biol., 16 (2):291-302
Tang S, Presgraves DC
Evolution of the Drosophila nuclear pore complex results in multiple hybrid incompatibilities.
2009 Feb, Science, 323 (5915):779-82

January, 2009

Gerke J, Lorenz K, Cohen B
Genetic interactions between transcription factors cause natural variation in yeast
2009 Jan, Science, 323(5913):498-501
Saccharomyces cerevisiae
Chipman K. C., Singh A. K.
Predicting genetic interactions with random walks on biological networks.
2009 Jan, BMC Bioinformatics, 10(1):17
discovery » techniques » computational prediction

December, 2008

November, 2008

October, 2008

Chan DA, Giaccia AJ
Targeting cancer cells by synthetic lethality: Autophagy and VHL in cancer therapeutics.
2008 Oct, Cell Cycle, 7(19). [Epub ahead of print]
concepts » synthetic lethality

applications » disease association studies » cancer

examples » synthetic lethality

Qi Y, Suhail Y, Lin YY, Boeke JD, Bader JS
Finding friends and enemies in an enemies-only network: A graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactions.
2008 Oct, Genome Res., [Epub ahead of print]
discovery » techniques » computational prediction

September, 2008

Järvinen AP, Hiissa J, Elo LL, Aittokallio T
Predicting quantitative genetic interactions by means of sequential matrix approximation.
2008 Sep, PLoS ONE, 3(9):e328
discovery » techniques » computational prediction
Roguev A, Bandyopadhyay S, Zofall M, Zhang K, Fischer T, Collins SR, Qu H, Shales M, Park HO, Hayles J, Hoe KL, Kim DU, Ideker T, Grewal SI, Weissman JS, Krogan NJ
Conservation and Rewiring of Functional Modules Revealed by an Epistasis Map in Fission Yeast.
2008 Sep, Science, [Epub ahead of print]Click here to read
discovery » techniques » pombe epistasis mapper (PEM)Schizosaccharomyces pombe
Le Meur N, Gentleman R
Modeling synthetic lethality.
2008 Sep, Genome Biol., 9(9):R135
interpretation & analysis
Casci T.
Functional genomics: An array of bacterial interactions
2008 Sep, Nat. Rev. Genet., 9:652-653
discovery » techniques

discovery » techniques

Escherichia coli

August, 2008

Pu S, Ronen K, Vlasblom J, Greenblatt J, Wodak SJ
Local Coherence in Genetic Interaction Patterns Reveals Prevalent Functional Versatility.
2008 Aug, Bioinformatics, [Epub ahead of print]
discovery » techniques » SGA » E-MAP

interpretation & analysis

Butland G, Babu M, Díaz-Mejía JJ, Bohdana F, Phanse S, Gold B, Yang W, Li J, Gagarinova AG, Pogoutse O, Mori H, Wanner BL, Lo H, Wasniewski J, Christopolous C, Ali M, Venn P, Safavi-Naini A, Sourour N, Caron S, Choi JY, Laigle L, Nazarians-Armavil A, Deshpande A, Joe S, Datsenko KA, Yamamoto N, Andrews BJ, Boone C, Ding H, Sheikh B, Moreno-Hagelseib G, Greenblatt JF, Emili A
eSGA: E. coli synthetic genetic array analysis.
2008 Aug, Nat. Methods, [Epub ahead of print]
discovery » techniquesEscherichia coli
Typas A, Nichols RJ, Siegele DA, Shales M, Collins SR, Lim B, Braberg H, Yamamoto N, Takeuchi R, Wanner BL, Mori H, Weissman JS, Krogan NJ, Gross CA
High-throughput, quantitative analyses of genetic interactions in E. coli.
2008 Aug, Nat. Methods, [Epub ahead of print]
discovery » techniquesEscherichia coli
Lin YY, Qi Y, Lu JY, Pan X, Yuan DS, Zhao Y, Bader JS, Boeke JD
A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation.
2008 Aug, Genes Dev., 22(15):2062-74
discovery » techniques » dSLAM
 


© 2007—2008 Anastasia Baryshnikova (a.baryshnikova@utoronto.ca), graduate student with Charlie Boone and Gary Bader at the University of Toronto.