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| Chipman K. C., Singh A. K. Predicting genetic interactions with random walks on biological networks. 2009 Jan, BMC Bioinformatics, 10(1):17 | discovery » techniques » computational prediction | |
| Chan DA, Giaccia AJ Targeting cancer cells by synthetic lethality: Autophagy and VHL in cancer therapeutics. 2008 Oct, Cell Cycle, 7(19). [Epub ahead of print] | concepts » synthetic lethality applications » disease association studies » cancer examples » synthetic lethality | |
| Qi Y, Suhail Y, Lin YY, Boeke JD, Bader JS Finding friends and enemies in an enemies-only network: A graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactions. 2008 Oct, Genome Res., [Epub ahead of print] | discovery » techniques » computational prediction | |
| Järvinen AP, Hiissa J, Elo LL, Aittokallio T Predicting quantitative genetic interactions by means of sequential matrix approximation. 2008 Sep, PLoS ONE, 3(9):e328 | discovery » techniques » computational prediction | |
| Roguev A, Bandyopadhyay S, Zofall M, Zhang K, Fischer T, Collins SR, Qu H, Shales M, Park HO, Hayles J, Hoe KL, Kim DU, Ideker T, Grewal SI, Weissman JS, Krogan NJ Conservation and Rewiring of Functional Modules Revealed by an Epistasis Map in Fission Yeast. 2008 Sep, Science, [Epub ahead of print]Click here to read | discovery » techniques » pombe epistasis mapper (PEM) | Schizosaccharomyces pombe |
| Le Meur N, Gentleman R Modeling synthetic lethality. 2008 Sep, Genome Biol., 9(9):R135 | interpretation & analysis | |
| Pu S, Ronen K, Vlasblom J, Greenblatt J, Wodak SJ Local Coherence in Genetic Interaction Patterns Reveals Prevalent Functional Versatility. 2008 Aug, Bioinformatics, [Epub ahead of print] | discovery » techniques » SGA » E-MAP interpretation & analysis | |
| Butland G, Babu M, Díaz-Mejía JJ, Bohdana F, Phanse S, Gold B, Yang W, Li J, Gagarinova AG, Pogoutse O, Mori H, Wanner BL, Lo H, Wasniewski J, Christopolous C, Ali M, Venn P, Safavi-Naini A, Sourour N, Caron S, Choi JY, Laigle L, Nazarians-Armavil A, Deshpande A, Joe S, Datsenko KA, Yamamoto N, Andrews BJ, Boone C, Ding H, Sheikh B, Moreno-Hagelseib G, Greenblatt JF, Emili A eSGA: E. coli synthetic genetic array analysis. 2008 Aug, Nat. Methods, [Epub ahead of print] | discovery » techniques | Escherichia coli |
| Lin YY, Qi Y, Lu JY, Pan X, Yuan DS, Zhao Y, Bader JS, Boeke JD A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. 2008 Aug, Genes Dev., 22(15):2062-74 | discovery » techniques » dSLAM | |
| Typas A, Nichols RJ, Siegele DA, Shales M, Collins SR, Lim B, Braberg H, Yamamoto N, Takeuchi R, Wanner BL, Mori H, Weissman JS, Krogan NJ, Gross CA High-throughput, quantitative analyses of genetic interactions in E. coli. 2008 Aug, Nat. Methods, [Epub ahead of print] | discovery » techniques | Escherichia coli |
| Dror O, Schneidman-Duhovny D, Shulman-Peleg A, Nussinov R, Wolfson HJ, Sharan R Structural similarity of genetically interacting proteins. 2008 Jul, BMC Syst. Biol, 2(1):69 | interpretation & analysis | |
| Gayan J, Gonzalez-Perez A, Bermudo F, Saez ME, Royo JL, Quintas A, Galan JJ, Moron FJ, Ramirez-Lorca R, Real LM, Ruiz A A method for detecting epistasis in genome-wide studies using case-control multi-locus association analysis. 2008 Jul, BMC Genomics, 9(1):360 | applications » disease association studies | |
| Ulitsky I, Shlomi T, Kupiec M, Shamir R From E-MAPs to module maps: dissecting quantitative genetic interactions using physical interactions. 2008 Jul, Mol. Syst. Biol., 4:209 | discovery » techniques » SGA » E-MAP interpretation & analysis | |
| McMurray HR, Sampson ER, Compitello G, Kinsey C, Newman L, Smith B, Chen SR, Klebanov L, Salzman P, Yakovlev A, Land H Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype. 2008 Jun, Nature, 453(7198):1112-1116 | applications » disease association studies » cancer | |
| Yukilevich R, Lachance J, Aoki F, True JR Long-term adaptation of epistatic genetic networks. 2008 Jun, Evolution, [Epub ahead of print] | applications » population genetics & evolution | |
| Pattin KA, Moore JH Exploiting the proteome to improve the genome-wide genetic analysis of epistasis in common human diseases. 2008 Jun, Hum. Genet., [Epub ahead of print] | applications » disease association studies | |
| Bandyopadhyay S, Kelley R, Krogan NJ, Ideker T Functional maps of protein complexes from quantitative genetic interaction data. 2008 Apr, PLoS Comput. Biol., 4(4):e1000065 | interpretation & analysis | |
| Qiu J, Noble WS Predicting co-complexed protein pairs from heterogeneous data. 2008 Apr, PLoS Comput. Biol., 4(4):e1000054 | interpretation & analysis | |
| Decourty L, Saveanu C, Zemam K, Hantraye F, Frachon E, Rousselle JC, Fromont-Racine M, Jacquier A Linking functionally related genes by sensitive and quantitative characterization of genetic interaction profiles. 2008 Apr, Proc. Natl. Acad. Sci. U.S.A., 105(15):5821-6 | discovery » techniques | |
| van Welsem T, Frederiks F, Verzijlbergen KF, Faber AW, Nelson Z, Egan DA, Gottschling DE, van Leeuwen F Synthetic lethal screens in yeast identify gene silencing pathways and implicate the acetylated amino terminus of Sir3 in recognition of the nucleosome core. 2008 Apr, Mol. Cell. Biol., [Epub ahead of print] | discovery » techniques » SGA | |
| Gale GD, Yazdi RD, Khan AH, Lusis AJ, Davis RC, Smith DJ A genome-wide panel of congenic mice reveals widespread epistasis of behavior quantitative trait loci. 2008 Apr, Mol. Psychiatry, [Epub ahead of print] | applications » disease association studies | Mus musculus |
| Jasnos L, Tomala K, Paczesniak D, Korona R Interactions between stressful environment and gene deletions alleviate the expected average loss of fitness in yeast. 2008 Apr, Genetics, 178(4):2105-11 | discovery | |
| Aylor DL, Zeng ZB From classical genetics to quantitative genetics to systems biology: modeling epistasis. 2008 Mar, PLoS Genet., 4(3):e1000029 | discovery » techniques » QTL + gene expression | |
| Chuang CL, Jen CH, Chen CM, Shieh GS A pattern recognition approach to infer time-lagged genetic interactions. 2008 Mar, Bioinformatics, 24(9):1183-90 | discovery » techniques » computational prediction | |
| Mechanic LE, Luke BT, Goodman JE, Chanock SJ, Harris CC Polymorphism Interaction Analysis (PIA): a method for investigating complex gene-gene interactions. 2008 Mar, BMC Bioinformatics, 9(1):146 | applications » disease association studies | |
| Shieh GS, Chen CM, Yu CY, Huang J, Wang WF, Lo YC Inferring transcriptional compensation interactions in yeast via stepwise structure equation modeling. 2008 Mar, BMC Bioinformatics, 9:134 | discovery » techniques » computational prediction | |
| Enomoto Y, Ushijima M, Miyata S, Matsuura M, Ohtaki M Inference on biological mechanisms using an integrated phenotype prediction model. 2008 Mar, Hiroshima J. Med. Sci., 57(1):7-15 | applications » prediction of gene function | |
| Ohkuni K, Abdulle R, Tong AH, Boone C, Kitagawa K Ybp2 Associates with the Central Kinetochore of Saccharomyces cerevisiae and Mediates Proper Mitotic Progression. 2008 Feb, PLoS ONE, 3(2):e1617 | discovery » techniques » SGA | |
| Hallgrimsdottir IB, Yuster DS A complete classification of epistatic two-locus models. 2008 Feb, BMC Genet., 9(1):17 | concepts » epistasis concepts applications » population genetics & evolution applications » disease association studies | |
| Bochdanovits Z, Sondervan D, Perillous S, van Beijsterveldt T, Boomsma D, Heutink P Genome-wide prediction of functional gene-gene interactions inferred from patterns of genetic differentiation in mice and men. 2008 Feb, PLoS ONE, 3(2):e1593 | applications » disease association studies | Homo sapiens, Mus musculus |
| Motter AE, Gulbahce N, Almaas E, Barabási AL Predicting synthetic rescues in metabolic networks. 2008 Feb, Mol. Syst. Biol., 4:168 | discovery » techniques » computational prediction » flux balance analysis (FBA) concepts » suppression | |
| Hintze A, Adami C Evolution of Complex Modular Biological Networks. 2008 Feb, PLoS Comput. Biol., 4(2):e23 | interpretation & analysis | |
| Motsinger-Reif AA, Dudek SM, Hahn LW, Ritchie MD Comparison of approaches for machine-learning optimization of neural networks for detecting gene-gene interactions in genetic epidemiology. 2008 Feb, Genet. Epidemiol., [Epub ahead of print] | applications » disease association studies | |
| Dickinson WJ Synergistic Fitness Interactions and a High Frequency of Beneficial Changes Among Mutations Accumulated Under Relaxed Selection in Saccharomyces cerevisiae. 2008 Feb, Genetics, [Epub ahead of print] | applications » population genetics & evolution | Saccharomyces cerevisiae |
| Frederick RL, Okamoto K, Shaw JM Multiple pathways influence mitochondrial inheritance in budding yeast. 2008 Feb, Genetics, 178(2):825-37 | discovery » techniques » SGA | |
| Yang J, Wu W, Zhu J Mapping interspecific genetic architecture in host-parasite interaction system. 2008 Feb, Genetics, [Epub ahead of print] | applications | |
| Kooperberg C., Leblanc M. Increasing the power of identifying gene x gene interactions in genome-wide association studies. 2008 Jan, Genet. Epidemiol., [Epub ahead of print] | applications » disease association studies | |
| Schoner D., Kalisch M., Leisner C., Meier L., Sohrmann M., Faty M., Barral Y., Peter M., Gruissem W., Buhlmann P. Annotating novel genes by integrating synthetic lethals and genomic information. 2008 Jan, BMC Syst. Biol, 2(1):3 | interpretation & analysis | |
| Nunkesser R., Bernholt T., Schwender H., Ickstadt K., Wegener I. Detecting high-order interactions of single nucleotide polymorphisms using genetic programming. 2007 Dec, Bioinformatics, 23(24):3280-3288 | applications » disease association studies | |
| Liberman U., Feldman M. On the evolution of epistasis III: The haploid case with mutation. 2007 Dec, Theor. Popul. Biol., [Epub ahead of print] | applications » population genetics & evolution | |
| Thornton-Wells T. A., Moore J. H., Martin E. R., Pericak-Vance M. A., Haines J. L. Confronting complexity in late-onset Alzheimer disease: application of two-stage analysis approach addressing heterogeneity and epistasis. 2007 Dec, Genet. Epidemiol., [Epub ahead of print] | applications » disease association studies examples » disease association studies | |
| Le Rouzic A., Carlborg O. Evolutionary potential of hidden genetic variation. 2007 Dec, Trends Ecol. Evol. (Amst.), [Epub ahead of print] | applications » population genetics & evolution | |
| Chen X, Liu CT, Zhang M, Zhang H A forest-based approach to identifying gene and gene gene interactions. 2007 Nov, Proc. Natl. Acad. Sci. U.S.A., 104(49):19199-19203 | applications » disease association studies | |
| Melchinger AE, Utz HF, Piepho HP, Zeng ZB, Schon CC. The role of epistasis in the manifestation of heterosis: a systems-oriented approach. 2007 Nov, Genetics, 177(3):1815-1825 | applications » population genetics & evolution » heterosis | |
| Dong C., Chu X., Wang Y., Wang Y., Jin L., Shi T., Huang W., Li Y. Exploration of gene-gene interaction effects using entropy-based methods. 2007 Oct, Eur. J. Hum. Genet., 16:229-235 | applications » disease association studies discovery » techniques concepts | |
| Kang G., Yue W., Zhang J., Cui Y., Zuo Y., Zhang D. An entropy-based approach for testing genetic epistasis underlying complex diseases. 2007 Oct, J. Theor. Biol., 250:362-374 | applications » disease association studies discovery » techniques | |
| Roguev A., Wiren M., Weissman J. S., Krogan N. J. High-throughput genetic interaction mapping in the fission yeast Schizosaccharomyces pombe. 2007 Oct, Nat. Methods, 4(10):861-866 | discovery » techniques » pombe epistasis mapper (PEM) | Schizosaccharomyces pombe |
| Byrne A. B., Weirauch M. T., Wong V., Koeva M., Dixon S. J., Stuart J. M., Roy P. J. A global analysis of genetic interactions in Caenorhabditis elegans. 2007 Sep, J. Biol., 6:8 | discovery » techniques » RNAi | Caenorhabditis elegans |
| Jain S, Stanford N, Bhagwat N, Seiler B, Costanzo M, Boone C, Oelkers P Identification of a novel lysophospholipid acyltransferase in Saccharomyces cerevisiae. 2007 Aug, J. Biol. Chem., 282(42):30562-30569 | discovery » techniques » SGA | |
| Desai M. M., Weissman D. B., Feldman M. W. Evolution can favor antagonistic epistasis. 2007 Aug, Genetics, 177(2):1001-1010 | applications » population genetics & evolution | |
| Foraita R., Bammann K., Pigeot I. Modeling gene-gene interactions using graphical chain models. 2007 Jul, Hum. Hered., 65(1):47-56 | discovery » techniques » computational prediction applications » population genetics & evolution | |
| Maccarthy T., Bergman A. Coevolution of robustness, epistasis, and recombination favors asexual reproduction. 2007 Jul, Proc. Natl. Acad. Sci. U.S.A., | applications » population genetics & evolution » evolution of sex & recombination | |
| Chapman J., Clayton D. Detecting association using epistatic information. 2007 Jul, Genet. Epidemiol., | applications » disease association studies | |
| Estrada-Gil J. K., Fernandez-Lopez J. C., Hernandez-Lemus E., Silva-Zolezzi I., Hidalgo-Miranda A., Jimenez-Sanchez G., Vallejo-Clemente E. E. GPDTI: a Genetic Programming Decision Tree Induction method to find epistatic effects in common complex diseases. 2007 Jul, Bioinformatics, 23(13):i167-i174 | discovery » techniques » computational prediction applications » disease association studies | |
| The Wellcome Trust Case Control Consortium Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. 2007 Jun, Nat. Genet., 447:661-678 | applications » disease association studies | Homo sapiens |
| Sepulveda N., Paulino C. D., Carneiro J., Penha-Goncalves C. Allelic penetrance approach as a tool to model two-locus interaction in complex binary traits. 2007 Jun, Heredity, 99(2):173-184 | applications » disease association studies | |
| Seo D. I., Moon B. R. An information-theoretic analysis on the interactions of variables in combinatorial optimization problems. 2007 Jun, Evol. Comput., 15(2):169-198 | interpretation & analysis | |
| Dettman J. R., Sirjusingh C., Kohn L. M., Anderson J. B. Incipient speciation by divergent adaptation and antagonistic epistasis in yeast. 2007 May, Nature, 447(7144):585-588 | applications » population genetics & evolution » speciation | Saccharomyces cerevisiae |
| Pickrell J., Clerget-Darpoux F., Bourgain C. Power of genome-wide association studies in the presence of interacting loci. 2007 May, Genet. Epidemiol., [Epub ahead of print] | applications » disease association studies | Homo sapiens |
| Yi N., Banerjee S., Pomp D., Yandell B. Bayesian mapping of genome-wide interacting QTL for ordinal traits. 2007 May, Genetics, [Epub ahead of print] | applications » disease association studies | Mus musculus |
| Ulitsky I., Shamir R. Pathway redundancy and protein essentiality revealed in the Saccharomyces cerevisiae interaction networks. 2007 Apr, Mol. Syst. Biol., 3:104 | interpretation & analysis applications » prediction of gene function | Saccharomyces cerevisiae |
| Beerenwinkel N., Pachter L., Sturmfels B., Elena S. F., Lenski R. E. Analysis of epistatic interactions and fitness landscapes using a new geometric approach. 2007 Apr, BMC Evol. Biol., 7(1):60 | applications » population genetics & evolution | |
| Collins S. R., Miller K. M., Maas N. L., Roguev A., Fillingham J., Chu C. S., Schuldiner M., Gebbia M., Recht J., Shales M., Ding H., Xu H., Han J., Ingvarsdottir K., Cheng B., Andrews B., Boone C., Berger S. L., Hieter P., Zhang Z., Brown G. W., Ingles C. J., Emili A., Allis C. D., Toczyski D. P., Weissman J. S., Greenblatt J. F., Krogan N. J. Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. 2007 Apr, Nature, 446(7137):806-810 | discovery » techniques » SGA » E-MAP | Saccharomyces cerevisiae |
| Park M. Y., Hastie T. Penalized logistic regression for detecting gene interactions. 2007 Apr, Biostatistics, 9(1):30-50 | interpretation & analysis applications » disease association studies | Homo sapiens |
| Memarian N., Jessulat M., Alirezaie J., Mir-Rashed N., Xu J., Zareie M., Smith M., Golshani A. Colony size measurement of the yeast gene deletion strains for functional genomics. 2007 Apr, BMC Bioinformatics, 8:117 | discovery » techniques » SGA » computational colony size measurement | Saccharomyces cerevisiae |
| Jasnos L., Korona R. Epistatic buffering of fitness loss in yeast double deletion strains. 2007 Apr, Nat. Genet., 39(4):550-554 | applications » population genetics & evolution | Saccharomyces cerevisiae |
| Martin G., Elena S. F., Lenormand T. Distributions of epistasis in microbes fit predictions from a fitness landscape model. 2007 Apr, Nat. Genet., 39(4):555-560 | applications » population genetics & evolution | Bacteria |
| Lin M., Li H., Hou W., Johnson J. A., Wu R. Modelling sequence-sequence interactions for drug response. 2007 Mar, Bioinformatics, 23(10):1251-1257 | discovery applications » disease association studies » drug response multiple perturbationsareas » chemical-genetic interactions » adverse drug response | Homo sapiens |
| Carter G. W., Prinz S., Neou C., Shelby J. P., Marzolf B., Thorsson V., Galitski T. Prediction of phenotype and gene expression for combinations of mutations. 2007 Mar, Mol. Syst. Biol., 3:96 | discovery » techniques » QTL + gene expression | Saccharomyces cerevisiae |
| Ihmels J., Collins S. R., Schuldiner M., Krogan N. J., Weissman J. S. Backup without redundancy: genetic interactions reveal the cost of duplicate gene loss. 2007 Mar, Mol. Syst. Biol., 3:86 | ||
| Menne TF, Goyenechea B, Sánchez-Puig N, Wong CC, Tonkin LM, Ancliff PJ, Brost RL, Costanzo M, Boone C, Warren AJ The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast. 2007 Mar, Nat. Genet., 39(4):486-495 | discovery » techniques » SGA | |
| Kouyos R. D., Silander O. K., Bonhoeffer S. Epistasis between deleterious mutations and the evolution of recombination. 2007 Mar, Trends Ecol. Evol. (Amst.), [Epub ahead of print] | applications » population genetics & evolution » evolution of sex & recombination | |
| Liberman U., Puniyani A., Feldman M. W. On the evolution of epistasis II: a generalized Wright-Kimura framework. 2007 Mar, Theor. Popul. Biol., 71(2):230-238 | applications » population genetics & evolution | |
| Hallander J., Waldmann P. The effect of non-additive genetic interactions on selection in multi-locus genetic models. 2007 Feb, Heredity, [Epub ahead of print] | applications » population genetics & evolution | |
| Harrison R., Papp B., Pal C., Oliver S. G., Delneri D. Plasticity of genetic interactions in metabolic networks of yeast. 2007 Feb, Proc. Natl. Acad. Sci. U.S.A., 104(7):2307-2312 | discovery » techniques » computational prediction » flux balance analysis (FBA) | |
| Onge R. P., Mani R., Oh J., Proctor M., Fung E., Davis R. W., Nislow C., Roth F. P., Giaever G. Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions. 2007 Feb, Nat. Genet., 39(2):199-206 | discovery interpretation & analysis | Saccharomyces cerevisiae |
| Haarer B., Viggiano S., Hibbs M. A., Troyanskaya O. G., Amberg D. C.
Modeling complex genetic interactions in a simple eukaryotic genome: actin displays a rich spectrum of complex haploinsufficiencies. 2007 Jan, Genes Dev., 21(2):148-159 | discovery » techniques » genomic haploinsufficiency modifier screen concepts » haploinsufficiency | Saccharomyces cerevisiae |
| Shah N. A., Laws R. J., Wardman B., Zhao L. P., Hartman J. L. IV Accurate, precise modeling of cell proliferation kinetics from time-lapse imaging and automated image analysis of agar yeast culture arrays. 2007 Jan, BMC Syst. Biol, 1:3 | discovery » techniques » SGA » computational colony size measurement | Saccharomyces cerevisiae |
| Gjuvsland A. B., Hayes B. J., Omholt S. W., Carlborg O.
Statistical epistasis is a generic feature of gene regulatory networks. 2007 Jan, Genetics, 175(1):411-420 | discovery » techniques » QTL + gene expression | |
| Lin E., Hwang Y., Liang K. H., Chen E. Y. Pattern-recognition techniques with haplotype analysis in pharmacogenomics. 2007 Jan, Pharmacogenomics, 8(1):75-83 | applications » disease association studies | |
| Meluh PB, Pan X, Yuan DS, Tiffany C, Chen O, Sookhai-Mahadeo S, Wang X, Peyser BD, Irizarry R, Spencer FA, Boeke JD Analysis of genetic interactions on a genome-wide scale in budding yeast: diploid-based synthetic lethality analysis by microarray. 2007 Jan, Methods Mol. Biol., 416:221-248 | discovery » techniques » dSLAM | |
| Jannink J. L. Identifying QTL by Genetic Background Interactions in Association Studies. 2006 Dec, Genetics, | ||
| Schuldiner M., Collins S. R., Weissman J. S., Krogan N. J. Quantitative genetic analysis in Saccharomyces cerevisiae using epistatic miniarray profiles (E-MAPs) and its application to chromatin functions. 2006 Dec, Methods, 40(4):344-252 | discovery » techniques » SGA » E-MAP | Saccharomyces cerevisiae |
| Brideau N. J., Flores H. A., Wang J., Shamoni Maheshwari S., Wang X., Barbash D. A. Two Dobzhansky-Muller Genes Interact to Cause Hybrid Lethality in Drosophila. 2006 Nov, Science, 314(5803):1292-1295 | applications » population genetics & evolution » speciation » Dobzhansky-Muller model | Drosophila melanogaster, Drosophila simulans |
| Welsh LM, Tong AH, Boone C, Jensen ON, Otte S Genetic and molecular interactions of the Erv41p-Erv46p complex involved in transport between the endoplasmic reticulum and Golgi complex. 2006 Oct, J. Cell Sci., 119(Pt 22):4730-4740 | discovery » techniques » SGA | |
| Sanjuan R., Elena S.F. Epistasis correlates to genomic complexity. 2006 Sep, Proc. Natl. Acad. Sci. U.S.A., 103(39):14402-14405 | applications » population genetics & evolution | Aspergillus niger, Saccharomyces cerevisiae, Drosophila melanogaster, Escherichia coli, Vesicular stomatitis virus (VSV) |
| Zhao J., Jin L., Xiong M. Test for interaction between two unlinked loci. 2006 Sep, Am. J. Hum. Genet., 79(5):831-845 | applications » disease association studies | |
| Deutscher D., Meilijson I., Kupiec M., Ruppin E. Multiple knockout analysis of genetic robustness in the yeast metabolic network. 2006 Sep, Nat. Genet., 38(9):993-998 | Saccharomyces cerevisiae | |
| Lehner B., Crombie C., Tischler J., Fortunato A., Fraser A. G. Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways. 2006 Aug, Nat. Genet., 38(8):896-903 | discovery » techniques » RNAi | Caenorhabditis elegans |
| Sopko R, Papp B, Oliver SG, Andrews BJ Phenotypic activation to discover biological pathways and kinase substrates. 2006 Jul, Cell Cycle, 5(13):1397-1402 | discovery » techniques » SDL | |
| Kouyos R. D., Otto S. P., Bonhoeffer S. Effect of varying epistasis on the evolution of recombination. 2006 Jun, Genetics, 173:589-597 | applications » population genetics & evolution » evolution of sex & recombination | |
| Blake D, Luke B, Kanellis P, Jorgensen P, Goh T, Penfold S, Breitkreutz BJ, Durocher D, Peter M, Tyers M The F-box protein Dia2 overcomes replication impedance to promote genome stability in Saccharomyces cerevisiae. 2006 May, Genetics, 174(4):1709-1727 | discovery » techniques » SGA | |
| Onay V. U., Briollais L., Knight J. A., Shi E., Wang Y., Wells S., Li H., Rajendram I., Andrulis I. L., Ozcelik H. SNP-SNP interactions in breast cancer susceptibility. 2006 May, BMC Cancer, 6:114 | applications » disease association studies » cancer | Homo sapiens |
| Pan X., Ye P., Yuan D.S., Wang X., Bader J.S., Boeke J.D. A DNA integrity network in the yeast Saccharomyces cerevisiae. 2006 Mar, Cell, 124(5):1069-1081 | discovery » techniques » dSLAM | Saccharomyces cerevisiae |
| Zhong W., Sternberg P.W. Genome-wide prediction of C. elegans genetic interactions. 2006 Mar, Science, 311:1481-1484 | discovery » techniques » computational prediction | Caenorhabditis elegans |
| Azevedo R. B., Lohaus R., Srinivasan S., Dang K. K., Burch C. L. Sexual reproduction selects for robustness and negative epistasis in aritifical gene networks. 2006 Mar, Nature, 440:87-90 | applications » population genetics & evolution » evolution of sex & recombination | |
| Baetz K., Measday V., Andrews B. Revealing hidden relationships among yeast genes involved in chromosome segregation using systematic synthetic lethal and synthetic dosage lethal screens. 2006 Mar, Cell Cycle, 5(6):592-595 | discovery » techniques » SGA discovery » techniques » SDL | Saccharomyces cerevisiae |
| Suzuki Y., Han M. Genetic redundancy masks diverse functions of the tumor suppressor gene PTEN during C. elegans development. 2006 Feb, Genes Dev., 20:423-428 | discovery » techniques » RNAi | Caenorhabditis elegans |
| Sopko R., Huang D., Preston N., Chua G., Papp B., Kafadar K., Snyder M., Oliver S. G., Cyert M., Hughes T. R., Boone C., Andrews B. Mapping pathways and phenotypes by systematic gene overexpression. 2006 Feb, Mol. Cell, 21:319-330 | discovery » techniques » SDL | Saccharomyces cerevisiae |
| Friesen H, Humphries C, Ho Y, Schub O, Colwill K, Andrews B Characterization of the yeast amphiphysins Rvs161p and Rvs167p reveals roles for the Rvs heterodimer in vivo. 2006 Jan, Mol. Biol. Cell, 17(3):1306-1321 | discovery » techniques » SGA | |
| Barbour L., Xiao W. Synthetic lethal screen. 2006 Jan, Methods Mol. Biol., 313:161-169 | discovery » techniques » plasmid dependency assay | Saccharomyces cerevisiae |
| Collins S.R., Schuldiner M., Krogan N.J., Weissman J.S. A strategy for extracting and analyzing large-scale quantitative epistatic interaction data. 2006 Jan, Genome Biol., 7:R63 | interpretation & analysis discovery » techniques » SGA » E-MAP | Saccharomyces cerevisiae |
| Tischler J., Lehner B., Chen N., Fraser A. G. Combinatorial RNA interference in C. elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution. 2006 Jan, Genome Biol., 7:R69 | discovery » techniques » RNAi | Caenorhabditis elegans |
| Kaufman A., Keinan A., Meilijson I., Kupiec M., Ruppin E. Quantitative analysis of genetic and neuronal multi-perturbation experiments. 2005 Nov, PLoS Comput. Biol., 1(6):e64 | interpretation & analysis multiple perturbationsareas | |
| Daniel JA, Keyes BE, Ng YP, Freeman CO, Burke DJ Diverse functions of spindle assembly checkpoint genes in Saccharomyces cerevisiae. 2005 Sep, Genetics, 172(1):53-65 | discovery » techniques » SGA | |
| Laribee RN, Krogan NJ, Xiao T, Shibata Y, Hughes TR, Greenblatt JF, Strahl BD BUR kinase selectively regulates H3 K4 trimethylation and H2B ubiquitylation through recruitment of the PAF elongation complex. 2005 Aug, Curr. Biol., 15(16):1487-1493 | discovery » techniques » SGA | |
| Milgrom E, West RW Jr, Gao C, Shen WC TFIID and Spt-Ada-Gcn5-acetyltransferase functions probed by genome-wide synthetic genetic array analysis using a Saccharomyces cerevisiae taf9-ts allele. 2005 Aug, Genetics, 171(3):959-793 | discovery » techniques » SGA | |
| Brem R. B., Storey J. D., Whittle J., Kruglyak L. Genetic interactions between polymorphisms that affect gene expression in yeast. 2005 Aug, Nature, 436(7051):701-703 | discovery » techniques » QTL + gene expression | |
| Wong S. L., Zhang L. V., Roth F. P. Discovering functional relationships: biochemistry versus genetics. 2005 Aug, Trends Genet., 21(8):424-427 | interpretation & analysis | Saccharomyces cerevisiae |
| Zhang L. V., King O. D., Wong S. L., Goldberg D. S., Tong A. H., Lesage G., Andrews B., Bussey H., Boone C., Roth F. P. Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction network. 2005 Jun, J. Biol., 4(2):6 | interpretation & analysis | Saccharomyces cerevisiae |
| Savchenko A, Krogan N, Cort JR, Evdokimova E, Lew JM, Yee AA, Sánchez-Pulido L, Andrade MA, Bochkarev A, Watson JD, Kennedy MA, Greenblatt J, Hughes T, Arrowsmith CH, Rommens JM, Edwards AM The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism. 2005 May, J. Biol. Chem., 280(19):19213-19220 | discovery » techniques » SGA | |
| Baugh L. R., Wen J. C., Hill A. A., Slonim D. K., Brown E. L., Hunter C. P. Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions. 2005 Apr, Genome Biol., 6(5):R45 | discovery » techniques » RNAi concepts » synthetic lethality | Caenorhabditis elegans |
| Pal G., Ultsch M. H., Clark K. P., Currell B., Kossiakoff A. A., Sidhu S. S. Intramolecular cooperativity in a protein binding site assessed by combinatorial shotgun scanning mutagenesis. 2005 Apr, J. Mol. Biol., 347(3):489-494 | examples | |
| Marchini J., Donnelly P., Cardon L. R. Genome-wide strategies for detecting multiple loci that influence complex diseases. 2005 Mar, Nat. Genet., 37(4):413-417 | concepts applications » disease association studies | |
| Zhao R, Davey M, Hsu YC, Kaplanek P, Tong A, Parsons AB, Krogan N, Cagney G, Mai D, Greenblatt J, Boone C, Emili A, Houry WA Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone. 2005 Mar, Cell, 120(5):715-727 | discovery » techniques » SGA | |
| Lesage G, Shapiro J, Specht CA, Sdicu AM, Ménard P, Hussein S, Tong AH, Boone C, Bussey H An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae. 2005 Feb, BMC Genet., 6(1):8 | discovery » techniques » SGA | |
| Brem R. B., Kruglyak L. The landscape of genetic complexity across 5,700 gene expression traits in yeast. 2005 Feb, Proc. Natl. Acad. Sci. U.S.A., 102(5):1572-1577 | discovery » techniques » QTL + gene expression | |
| Ingvarsdottir K, Krogan NJ, Emre NC, Wyce A, Thompson NJ, Emili A, Hughes TR, Greenblatt JF, Berger SL H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex. 2005 Feb, Mol. Biol. Cell, 25(3):1162-1172 | discovery » techniques » SGA | |
| Davierwala A. P., Haynes J., Li Z., Brost R. L., Robinson M. D., Yu L., Mnaimneh S., Ding H., Zhu H., Chen Y., Cheng X., Brown G. W., Boone C., Andrews B. J., Hughes T. R. The synthetic genetic interaction spectrum of essential genes. 2005 Jan, Nat. Genet., 37(10):1147-1152 | discovery » techniques » SGA | Saccharomyces cerevisiae |
| Drees B.L., Thorsson V., Carter G.W., Rives A.W., Raymond M.Z., Avila-Campillo I., Shannon P., Galitski T. Derivation of genetic interaction networks from quantitative phenotype data. 2005 Jan, Genome Biol., 6:R38 | ||
| Juvan P., Demsar J., Shaulsky G., Zupan B. GenePath: from mutations to genetic networks and back. 2005 Jan, Nucleic Acids Res., 33(Web Server issue):W749-52 | interpretation & analysis » techniques » GenePath discovery » techniques » computational prediction | Dyctyostelium discoideum |
| Kelley R., Ideker T. Systematic interpretation of genetic interactions using protein networks. 2005 Jan, Nat. Biotechnol., 23(5):561-566 | interpretation & analysis | |
| Measday V., Baetz K., Guzzo J., Yuen K., Kwok T., Sheikh B., Ding H., Ueta R., Hoac T., Cheng B., Pot I., Tong A., Yamaguchi-Iwai Y., Boone C., Hieter P., Andrews B.
Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation. 2005 Jan, Proc. Natl. Acad. Sci. U.S.A., 102(39):13956-13961 | discovery » techniques » SGA discovery » techniques » SDL | Saccharomyces cerevisiae |
| Moore J. H., Williams S. M. Traversing the conceptual divide between biological and statistical epistasis: systems biology and a more modern synthesis. 2005 Jan, Bioessays, 27:637-646 | ||
| Qi Y., Ye P., Bader J. S. Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthetic lethality. 2005 Jan, BMC Bioinformatics, 6:288 | interpretation & analysis » techniques » GIMF concepts » synthetic lethality | Saccharomyces cerevisiae |
| Schuldiner M., Collins S.R., Thompson N.J., Denic V., Bhamidipati A., Punna T., Ihmels J., Andrews B., Boone C., Greenblatt J.F., Weissman J.S., Krogan N.J. Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. 2005 Jan, Cell, 123:507-519 | discovery » techniques » SGA » E-MAP | Saccharomyces cerevisiae |
| Segre D., Deluna A., Church G.M., Kishony R. Modular epistasis in yeast metabolism. 2005 Jan, Nat. Genet., 37(1):77-83 | discovery » techniques » computational prediction » flux balance analysis (FBA) | Saccharomyces cerevisiae |
| Van Driessche N., Demsar J., Booth E. O., Hill P., Juvan P., Zupan B., Kuspa A., Shaulsky G.
Epistasis analysis with global transcriptional phenotypes. 2005 Jan, Nat. Genet., 37(5):471-477 | concepts » epistasis discovery » techniques » QTL + gene expression | Dyctyostelium discoideum |
| Xiao T, Kao CF, Krogan NJ, Sun ZW, Greenblatt JF, Osley MA, Strahl BD Histone H2B ubiquitylation is associated with elongating RNA polymerase II. 2005 Jan, Mol. Cell. Biol., 25(2):637-651 | discovery » techniques » SGA | |
| Yamada T., Kawashima S., Mamitsuka H., Goto S., Kanehisa M. Comprehensive analysis and prediction of synthetic lethality using subcellular locations. 2005 Jan, Genome Inform., 16(1):150-158 | interpretation & analysis concepts » synthetic lethality | Saccharomyces cerevisiae |
| Ye P., Peyser B. D., Pan X., Boeke J. D., Spencer F. A., Bader J. S.
Gene function prediction from congruent synthetic lethal interactions in yeast. 2005 Jan, Mol. Syst. Biol., 1:2005.0026 | concepts » synthetic lethality interpretation & analysis | Saccharomyces cerevisiae |
| Ye P., Peyser B. D., Spencer F. A., Bader J. S. Commensurate distances and similar motifs in genetic congruence and protein interaction networks in yeast. 2005 Jan, BMC Bioinformatics, 6:270 | interpretation & analysis | |
| Puniyani A., Liberman U., Feldman M. W. On the meaning of non-epistatic selection. 2004 Dec, Theor. Popul. Biol., 66(4):317-321 | applications » population genetics & evolution | |
| Sciorra VA, Audhya A, Parsons AB, Segev N, Boone C, Emr SD Synthetic genetic array analysis of the PtdIns 4-kinase Pik1p identifies components in a Golgi-specific Ypt31/rab-GTPase signaling pathway. 2004 Dec, Mol. Biol. Cell, 16(2):776-793 | discovery » techniques » SGA | |
| Sarin S, Ross KE, Boucher L, Green Y, Tyers M, Cohen-Fix O Uncovering novel cell cycle players through the inactivation of securin in budding yeast. 2004 Nov, Genetics, 168(3):1763-1771 | discovery » techniques » SGA | |
| Van Haaften G., Vastehouw N. L., Nollen E. A., Plasterk R. H., Tijsterman M. Gene interactions in the DNA damage-response pathway identified by genome-wide RNA-interference analysis of synthetic lethality. 2004 Aug, Proc. Natl. Acad. Sci. U.S.A., 101(35):12992-12996 | discovery » techniques » RNAi concepts » synthetic lethality | Caenorhabditis elegans |
| Lesage G, Sdicu AM, Ménard P, Shapiro J, Hussein S, Bussey H Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin. 2004 May, Genetics, 167(1):35-49 | discovery » techniques » SGA | |
| Mayer ML, Pot I, Chang M, Xu H, Aneliunas V, Kwok T, Newitt R, Aebersold R, Boone C, Brown GW, Hieter P Identification of protein complexes required for efficient sister chromatid cohesion. 2004 Jan, Mol. Biol. Cell, 15(4):1736-1745 | discovery » techniques » SGA | |
| Baetz K. K., Krogan N. J., Emili A., Greenblatt J., Hieter P. The ctf13-30/CTF13 Genomic Haploinsufficiency Modifier Screen Identifies the Yeast Chromatin Remodeling Complex RSC, Which Is Required for the Establishment of Sister Chromatid Cohesion. 2004 Jan, Mol. Cell. Biol., 24(3):1232-1244 | discovery » techniques » genomic haploinsufficiency modifier screen | Saccharomyces cerevisiae |
| Hartman J. L. IV, Tippery N. P. Systematic quantification of gene interactions by phenotypic array analysis. 2004 Jan, Genome Biol., 5(7):R49 | discovery | Saccharomyces cerevisiae |
| Hartwell L. Robust interactions. 2004 Jan, Science, 303(5659):774-775 | concepts » synthetic lethality | |
| Moore J. H., Hahn L. W., Ritchie M. D., Thornton T. A., White B. C. Routine discovery of complex genetic models using genetic algorithms. 2004 Jan, Appl. Soft Comput., 4:79-86 | concepts applications » disease association studies | |
| Pan X, Yuan DS, Xiang D, Wang X, Sookhai-Mahadeo S, Bader JS, Hieter P, Spencer F, Boeke JD. A robust toolkit for functional profiling of the yeast genome. 2004 Jan, Mol. Cell, 16(3):487-496 | discovery » techniques » dSLAM | Saccharomyces cerevisiae |
| Sanjuan R., Moya A., Elena S. F. The contribution of epistasis to the architecture of fitness in an RNA virus. 2004 Jan, Proc. Natl. Acad. Sci. U.S.A., 101(43):15376-15379 | Vesicular stomatitis virus (VSV) | |
| Tong A.H.Y., Lesage G., Bader G.D., Ding H., Xu H., Xin X., Young J., Berriz G.F., Brost R.L., Chang M., Chen Y.Q., Cheng X., Chua G., Friesen H., Goldberg D.S., Haynes J., Humphries C., He G., Hussein S., Ke L., Krogan N., Li Z., Levinson J.N., Lu H., Me´nard P., Munyana,C., Parsons A.B., Ryan O., Tonikian R., Roberts T., Sdicu A.-M., Shapiro J., Sheikh B., Suter B., Wong S.L., Zhang L.V., Zhu H., Burd C.G., Munro S., Sander C., Rine J., Greenblatt J., Peter M., Bretscher A., Bell G., Roth F.P., Brown G.W., Andrews B., Bussey H., Boone C. Global Mapping of the Yeast Genetic Interaction Network. 2004 Jan, Science, 303:808-813 | discovery » techniques » SGA | Saccharomyces cerevisiae |
| Wagner A. Reconstructing pathways in large genetic networks from genetic perturbations. 2004 Jan, J. Comput. Biol., 11:53-60 | ||
| Wong S. L., Zhang L. V., Tong A. H., Li Z., Goldberg D. S., King O. D., Lesage G., Vidal M., Andrews B., Bussey H., Boone C., Roth F. P. Combining biological networks to predict genetic interactions. 2004 Jan, Proc. Natl. Acad. Sci. U.S.A., 101(44):15682-15687 | discovery » techniques » computational prediction | |
| Xu H., Boone C., Klein H.L. Mrc1 is required for sister chromatid cohesion to aid in recombination repair of spontaneous damage 2004 Jan, Mol. Cell. Biol., 24(16):7082-7090 | discovery » techniques » SGA | |
| Krogan NJ, Keogh MC, Datta N, Sawa C, Ryan OW, Ding H, Haw RA, Pootoolal J, Tong A, Canadien V, Richards DP, Wu X, Emili A, Hughes TR, Buratowski S, Greenblatt JF A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. 2003 Dec, Mol. Cell, 12(6):1565-1576 | discovery » techniques » SGA | |
| Krogan NJ, Kim M, Tong A, Golshani A, Cagney G, Canadien V, Richards DP, Beattie BK, Emili A, Boone C, Shilatifard A, Buratowski S, Greenblatt J Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II. 2003 Jun, Mol. Cell. Biol., 23(12):4207-18 | discovery » techniques » SGA | |
| Goehring A. S., Mitchell D. A., Tong A. H., Keniry M. E., Boone C., Sprague G. F. Jr. Synthetic lethal analysis implicates Ste20p, a p21-activated protein kinase, in polarisome activation. 2003 Apr, Mol. Biol. Cell, 14(4):1501-1516 | examples » synthetic lethality » enzyme-substrate relationship discovery » techniques » SGA | Saccharomyces cerevisiae |
| Bader J. S. Greedily building protein networks with confidence. 2003 Jan, Bioinformatics, 19:1869-1874 | applications » prediction of gene function | |
| Farrall M. Reports of the Death of the Epistasis Model Are Greatly Exaggerated. 2003 Jan, Am. J. Hum. Genet., 73(6):1467-1468 | applications » disease association studies | |
| Kamb A. Mutation load, functional overlap, and synthetic lethality in the evolution and treatment of cancer. 2003 Jan, J. Theor. Biol., 223(2):205-213 | applications » disease association studies » cancer | |
| Koren A., Ben-Aroya S., Steinlauf R., Kupiec M. Pitfalls of the synthetic lethality screen in Saccharomyces cerevisiae: an improved design. 2003 Jan, Curr. Genet., 43(1):62-69 | discovery » techniques » plasmid dependency assay | Saccharomyces cerevisiae |
| Moore J. H. The ubiquitous nature of epistasis in determining susceptibility to common human diseases. 2003 Jan, Hum. Hered., 56(1-3):73-82 | applications » disease association studies | Homo sapiens |
| Ooi S. L., Shoemaker D. D., Boeke J. D. DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray. 2003 Jan, Nat. Genet., 35:277-286 | discovery » techniques » SLAM | |
| Ozier O., Amin N., Ideker T. Global architecture of genetic interactions on the protein network. 2003 Jan, Nat. Biotechnol., 21(5):490-491 | interpretation & analysis | |
| Szafraniec K., Wloch D. M., Sliwa P., Borts R. H., Korona R. Small fitness effects and weak genetic interactions between deleterious mutations in heterozygous loci of the yeast Saccharomyces cerevisiae. 2003 Jan, Genet. Res., 82(1):19-31 | discovery | Saccharomyces cerevisiae |
| Vieland V. J., Huang J. Two-Locus Heterogeneity Cannot Be Distinguished from Two-Locus Epistasis on the Basis of Affected-Sib-Pair Data. 2003 Jan, Am. J. Hum. Genet., 73(2):223-232 | applications » disease association studies | |
| Zupan B., Bratko I., Demsar J., Juvan P., Curk T., Borstnik U., Beck J. R., Halter J., Kuspa A., Shaulsky G. GenePath: a system for inference of genetic networks and proposal of genetic experiments. 2003 Jan, Artif. Intell. Med., 29(1-2):107-130 | interpretation & analysis » techniques » GenePath discovery » techniques » computational prediction | Dyctyostelium discoideum |
| Zupan B., Demsar J., Bratko I., Juvan P., Halter J. A., Kuspa A., Shaulsky G.
GenePath: a system for automated construction of genetic networks from mutant data. 2003 Jan, Bioinformatics, 19(3):383-389 | discovery » techniques » computational prediction interpretation & analysis » techniques » GenePath | |
| Huang D, Moffat J, Andrews B Dissection of a complex phenotype by functional genomics reveals roles for the yeast cyclin-dependent protein kinase Pho85 in stress adaptation and cell integrity. 2002 Jul, Mol. Cell. Biol., 22(14):5076-88 | discovery » techniques » SGA | |
| Jorgensen P., Nelson B., Robinson M.D., Chen Y., Andrews B., Tyers M., Boone C. High-Resolution Genetic Mapping With Ordered Arrays of Saccharomyces cerevisiae Deletion Mutants. 2002 Jan, Genetics, 162:1091-1099 | discovery » techniques » SGA | Saccharomyces cerevisiae |
| Measday V., Hieter P. Synthetic dosage lethality. 2002 Jan, Meth. Enzymol., 350:316-326 | discovery » techniques » SDL | |
| Nigavekar S. S., Cannon J. F. Characterization of genes that are synthetically lethal with ade3 or leu2 in Saccharomyces cerevisiae. 2002 Jan, Yeast, 19(2):115-122 | discovery » techniques » plasmid dependency assay | Saccharomyces cerevisiae |
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| Mullen J.R., Kaliraman V., Ibrahim S.S., Brill S.J. Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae. 2001 Jan, Genetics, 157:103-118 | discovery » techniques » plasmid dependency assay | Saccharomyces cerevisiae |
| Ritchie M.D., Hahn L.W., Roodi N., Renee Bailey L.R., Dupont W.D., Parl F.F., Moore J.H. Multifactor-Dimensionality Reduction Reveals High-Order Interactions among Estrogen-Metabolism Genes in Sporadic Breast Cancer. 2001 Jan, Am. J. Hum. Genet., 69:138-147 | applications » disease association studies discovery » techniques | Homo sapiens |
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Systematic genetic analysis with ordered arrays of yeast deletion mutants. 2001 Jan, Science, 294(5550):2364-2368 | discovery » techniques » SGA | Saccharomyces cerevisiae |
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| Barbour L., Zhu Y., Xiao W. Improving synthetic lethal screens by regulating the yeast centromere sequence. 2000 Jan, Genome, 43(5):910-917 | discovery » techniques » plasmid dependency assay | Saccharomyces cerevisiae |
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| de Visser J. A., Hoekstra R. F., van den Ende H. An experimental test for synergistic epistasis and its application in Chlamydomonas. 1997 Jan, Genetics, 145(3):815-819 | Chlamydomonas moewusii | |
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